In recent years, the discovery of new classes and modifications of RNA has ushered in a renaissance of RNA-focused research. Did you know that NEB offers a broad portfolio of reagents for the purification, quantitation, detection, synthesis and manipulation of RNA? Experience improved performance and increased yields, enabled by our expertise in enzymology.

Transform your nucleic acid purification experience with Monarch®

Quickly and easily purify up to 100 µg of high quality total RNA from multiple sample types – all with one kit!

  • Use with blood, cells, tissues and tough-to-lyse samples
  • Effectively purify total RNA of all sizes, including small RNA (<200 nt)
  • Efficiently remove genomic DNA, as our Monarch Total RNA Miniprep Kit includes gDNA Removal Columns and DNase I

Learn more and request a sample

Optimize your RT-qPCR with Luna®

Experience superior performance across a wide variety of sample types

  • Increased thermostability with our novel reverse transcriptase
  • Non-interfering visible tracking dye helps to eliminate pipetting errors

Try a sample and see how Luna outperforms the competition

Get even more from less with NEBNext® Ultra™ II Library Prep for RNA-seq

Generate high-quality libraries even with limited amounts of RNA

  • Save time with streamlined workflows, reduced hands-on time and automation compatibility
  • Order reagents specific to your needs, including directional and non-directional kits, rRNA depletion and poly(A) mRNA isolation
    reagents, and adaptors and primers (12- and 96-index) sold separately
  • Working with Small RNA? Minimize adaptor-dimer formation while achieving high yield, diverse multiplex libraries with our unique Small RNA library preparation workflow.

View performance data and request a free sample

Synthesize high-quality RNA with reagents designed to simplify your workflow

One or more of these products are covered by patents, trademarks and/or copyrights owned or controlled by New England Biolabs, Inc. For more information, please email us at gbd@neb.com. The use of these products may require you to obtain additional third party intellectual property rights for certain applications.

Get started with these RNA-related references:

RNA Synthesis Brochure
Learn more about NEB's products for synthesis of RNA, which range from template generation to poly(A) tailing.

Monarch Nucleic Acid Purification Brochure
It’s time to transform your DNA and RNA purification experience! Learn about the advantages of choosing Monarch Nucleic Acid Purification Kits from NEB.

Luna Universal qPCR And RT-qPCR Brochure
Make a simpler choice with Luna! Learn about the advantages of choosing Luna products for your qPCR & RT-qPCR, and see how Luna products compare to other commercially available reagents.

NEBNext for Illumina Brochure
Review NEB's extensive range of NGS sample prep products for RNA, Small RNA and DNA.

RNA Metro Map Poster
Download our RNA poster to learn more about the various RNA structures and recent applications.

  1. RNase_Contamination_Anim_720x405

    Avoiding RNase Contamination

    Learn about the sources of RNase contamination and how you can prevent them from disrupting your experiments.

  2. NEBNextVideo_OptimizingRNAInput_thumb

    Tips for Optimizing RNA Inputs in NGS Library Construction

    Watch as Deyra explains how to optimize your RNA inputs for successful NGS library preparation.

  3. NEBNextUltra2DirectionalRNA_720

    NEBNext Ultra II Directional RNA Workflow

    Learn more about the streamlined workflow for the NEBNext Ultra II Directional RNA Library Prep Kit.

  4. NEBTv_Ep16_Thumb

    NEB TV Episode 16

    Learn the basics of qPCR, and hear more about our Luna products, including our novel method for data analysis.