FAQ: Does WarmStart Afu Uracil-DNA Glycosylase (UDG) cut RNA?

No, WarmStart Afu Uracil-DNA Glycosylase (UDG) should not act on an RNA substrate. UDG enzymes evolved to repair dU residues in DNA that can be created by deamination of dC (hence avoiding the mutation of a C:G base pair to T:A that would occur when the U-strand was replicated).
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